Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | PPARD | Q03181 | 1/20 | 0.57 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11454395 | 0.83 | PPARG (0.45) | PPARGPPARDPPARATSHRNFKB1 | |
| SCHEMBL9570755 | 0.79 | ABCB11 (0.46) | TSHRCYP1A2CYP2C9CYP2C19NPSR1 | |
| SCHEMBL7120860 | 0.77 | PPARG (0.53) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL10902404 | 0.77 | PPARG (0.66) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL9570766 | 0.75 | AOC3 (0.48) | TSHRSMN1; SMN2KMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL22785859 | 0.75 | CYP3A4 (0.74) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL8867400 | 0.75 | PPARG (0.64) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL22785862 | 0.75 | CYP3A4 (0.74) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL1655319 | 0.75 | CYP3A4 (0.74) | PPARGPPARDPPARATSHRCYP3A4 | |
| SCHEMBL9570629 | 0.75 | KDM1A (0.40) | CYP1A2CYP2C9CYP2C19KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0545891-A2 | Aldehyde compounds and derivatives thereof useful as intermediates in the preparation of insectical ether compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-06-09 | — | — | EP | disclosed |
| US-4840971-A | INSECTICIDES, MITICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-06-20 | — | — | US | disclosed |
| EP-0240978-A2 | Ether compounds, process for their preparation, compositions containing the same and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-14 | — | — | EP | disclosed |