Formanilide

Formanilide

SCHEMBL9570929

O=CNc1ccccc1.[KH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.94
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
TDP1 Q9NUW8 3/20 0.43
HSD17B10 Q99714 2/20 0.43
CTSD P07339 1/20 0.43
TSHR P16473 4/20 0.42
LMNA P02545 2/20 0.42
PTGS2 P35354 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
PTGS1 P23219 1/20 0.41
SLC6A2 P23975 1/20 0.41
MAPK1 P28482 1/20 0.41
HTR2B P41595 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formanilide SCHEMBL2463 0.97
Formanilide SCHEMBL29177030 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
SCHEMBL23353504 0.97 ALDH1A1 (1.00) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL10608400 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL2543681 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL10886951 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL569206 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL11419741 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL11116637 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A
Formanilide SCHEMBL30551758 0.94 ALDH1A1 (0.94) ALDH1A1SMN1; SMN2NPC1NFKB1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0148145-B1 PROCESS FOR MAKING NITRODIARYLAMINES Monsanto Company (US) 1986-12-30 EP claimed
EP-0148145-A1 Process for making nitrodiarylamines Monsanto Company (US) 1985-07-10 EP claimed
US-4187248-A FORMANILIDE MONSANTO COMPANY (US) 1980-02-05 US claimed
US-4187249-A COMPOUNDS OF POTASSIUM, CESIUM, OR RUBIDIUM MONSANTO COMPANY (US) 1980-02-05 US claimed
US-4140716-A Process for making an amide of formic acid and forming nitrodiarylamine therefrom MONSANTO COMPANY (US) 1979-02-20 US claimed
EP-0566783-A1 Process for the production of nitrodiarylamines AKZO N.V. (NL) 1993-10-27 EP disclosed
EP-0147379-B1 MAKING NITRODIARYLAMINES MONSANTO COMPANY (US) 1987-07-01 EP disclosed
EP-0148145-B1 PROCESS FOR MAKING NITRODIARYLAMINES Monsanto Company (US) 1986-12-30 EP disclosed
US-4614817-A FORMYLANILIDES, NITROHALOARENOS AND ALKOXIDES MONSANTO COMPANY (US) 1986-09-30 US disclosed
US-4595781-A N,N'-dithiobisformanilides and their use in diene rubber MONSANTO COMPANY (US) 1986-06-17 US disclosed
EP-0148145-A1 Process for making nitrodiarylamines Monsanto Company (US) 1985-07-10 EP disclosed
EP-0147379-A1 Making nitrodiarylamines MONSANTO COMPANY (US) 1985-07-03 EP disclosed
US-4391953-A Diene rubber compositions containing N,N'-dithioformanilide crosslinkers MONSANTO COMPANY (US) 1983-07-05 US disclosed
US-4228103-A Effecting condensation of nitrohaloarene and formyl derivative of a primary aromatic amine with alkali metal hydroxide MONSANTO COMPANY (US) 1980-10-14 US disclosed
US-4209463-A Promoting the formation of nitrodiarylamines from nitrohaloarenes, activated aryl amines and sodium carbonates MONSANTO COMPANY (US) 1980-06-24 US disclosed
US-4187248-A FORMANILIDE MONSANTO COMPANY (US) 1980-02-05 US disclosed
US-4187249-A COMPOUNDS OF POTASSIUM, CESIUM, OR RUBIDIUM MONSANTO COMPANY (US) 1980-02-05 US disclosed
US-4140716-A Process for making an amide of formic acid and forming nitrodiarylamine therefrom MONSANTO COMPANY (US) 1979-02-20 US disclosed