Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9571033 | 0.84 | KDM4E (0.40) | KDM4EHPGDALDH1A1GAAGALR3 | |
| SCHEMBL9571037 | 0.81 | IDH1 (0.38) | KDM4EHPGDALDH1A1GAAGALR3 | |
| SCHEMBL9566905 | 0.73 | KDM4E (0.46) | KDM4EHPGDALDH1A1GAAGLA | |
| SCHEMBL26528667 | 0.70 | GRIN1 (0.37) | KDM4EHPGDALDH1A1GABRG2GABRB3 | |
| SCHEMBL26528676 | 0.69 | GRIN1 (0.36) | KDM4EHPGDALDH1A1GABRG2GABRB3 | |
| SCHEMBL17949576 | 0.69 | KDM4E (0.38) | KDM4EALDH1A1GAAGABRG2GABRB3 | |
| SCHEMBL26529531 | 0.67 | ESR2 (0.38) | KDM4EHPGDALDH1A1GABRG2GABRB3 | |
| SCHEMBL29662936 | 0.66 | ESR2 (0.53) | KDM4EHPGDALDH1A1GAAGALR3 | |
| SCHEMBL28133054 | 0.66 | ESR2 (0.53) | KDM4EHPGDALDH1A1GAAGALR3 | |
| SCHEMBL31663533 | 0.66 | PDE9A (0.39) | KDM4EALDH1A1GABRG2GABRB3GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0530702-A1 | 1,2-dihydro-2-oxopyridines as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-03-10 | — | — | EP | disclosed |