Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28913319 | 0.80 | IMPDH2 (0.42) | KDM4EALDH1A1MEN1KMT2AIMPDH2 | |
| SCHEMBL9571033 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL19697253 | 0.75 | TRPA1 (0.40) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL17949576 | 0.75 | KDM4E (0.38) | KDM4EALDH1A1GLAGAATSHR | |
| SCHEMBL9571037 | 0.74 | IDH1 (0.38) | KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18347464 | 0.74 | DUSP3 (0.38) | KDM4EALDH1A1MEN1KMT2AIMPDH2 | |
| SCHEMBL19697300 | 0.74 | IMPDH2 (0.37) | KDM4EALDH1A1MEN1KMT2AIMPDH2 | |
| SCHEMBL18347465 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL18347467 | 0.74 | KDM4E (0.38) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9570955 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561252-A1 | 2-Oxoquinoline derivatives as angiotensin II antagonists | MERCK PATENT GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |