Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | P4HB | P07237 | 4/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | CCND1 | P24385 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572014 | 0.83 | PTPRC (0.78) | PTPRCBACE1CCNT1CDK9CCNE2 | |
| SCHEMBL31194258 | 0.83 | PTPRC (0.78) | PTPRCBACE1CCNT1CDK9CCNE2 | |
| SCHEMBL9572025 | 0.78 | PTPRC (0.74) | PTPRCBACE1CCNT1CDK9CCNE2 | |
| SCHEMBL6237555 | 0.77 | PTPRC (1.00) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| SCHEMBL9572021 | 0.73 | PTPRC (0.60) | PTPRCBACE1CCNT1CDK9CCNE2 | |
| SCHEMBL7716530 | 0.72 | PTPRC (0.62) | PTPRCCCNT1CDK9AURKAAURKB | |
| SCHEMBL9562546 | 0.71 | BACE1 (0.57) | PTPRCBACE1P4HBAURKAAURKB | |
| SCHEMBL10791127 | 0.70 | PTPRC (0.62) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| SCHEMBL6098441 | 0.69 | CCNT1 (0.57) | PTPRCCCNT1CDK9CCNE2CDK4 | |
| SCHEMBL10436037 | 0.68 | PTPRC (0.60) | PTPRCCCNT1CDK9CCNE2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |