Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.78 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.50 |
| ▸ | CDK9 | P50750 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31194258 | 1.00 | PTPRC (0.78) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572025 | 0.94 | PTPRC (0.74) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL6237555 | 0.88 | PTPRC (1.00) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572021 | 0.86 | PTPRC (0.60) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572018 | 0.83 | PTPRC (0.62) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL7716530 | 0.83 | PTPRC (0.62) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL9572020 | 0.78 | PTPRC (0.53) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL10791127 | 0.77 | PTPRC (0.62) | PTPRCCDK2CCNE2CDK4CCND1 | |
| SCHEMBL28336955 | 0.76 | SIRT2 (0.55) | PTPRCBACE1MEN1USP2ALDH1A1 | |
| SCHEMBL28336966 | 0.76 | PTPRC (0.48) | PTPRCBACE1GSK3BMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| CN-110437124-B | Preparation method of indoloquinone derivative | 中国科学院成都有机化学有限公司 | 2020-12-22 | — | — | CN | disclosed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |