SCHEMBL95736

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL95029	1.00	HPGD (0.80)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL2538732	0.98	HPGD (0.76)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL7132525	0.89	HPGD (1.00)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL27479149	0.89	HPGD (1.00)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL10721733	0.87	HPGD (0.95)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL95490	0.84	L3MBTL3 (0.85)	ALDH1A1KMT2AMEN1MBTD1L3MBTL3
	SCHEMBL2539905	0.83	HPGD (0.71)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL95807	0.83	L3MBTL3 (0.68)	HPGDALDH1A1KMT2AMEN1MBTD1
	SCHEMBL4050706	0.82	HPGD (0.83)	HPGDALDH1A1KMT2AMEN1TSHR
	SCHEMBL3905925	0.82	HPGD (0.83)	HPGDALDH1A1KMT2AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.