Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.88 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Peroxide SCHEMBL9143793 | 0.97 | — | — | |
| SCHEMBL28118128 | 0.94 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| Acetic Acid SCHEMBL10579414 | 0.94 | ALDH1A1 (0.88) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| SCHEMBL1849 | 0.94 | — | — | |
| SCHEMBL27466495 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| SCHEMBL10636466 | 0.94 | — | — | |
| SCHEMBL4390490 | 0.94 | ALDH1A1 (1.00) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| Methacrylic Acid SCHEMBL10493520 | 0.92 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| Methacrylic Acid SCHEMBL1171642 | 0.92 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1THRBEGLN1 | |
| SCHEMBL8640314 | 0.92 | ALDH1A1 (0.83) | ALDH1A1TSHRTDP1THRBEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230369563-A1 | NEGATIVE ELECTRODE SHEET AND LITHIUM-ION BATTERY INCLUDING SAME | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2023-11-16 | — | — | US | claimed |
| CN-109387622-A | A kind of polymer surface method of modifying and its application | 国家纳米科学中心 | 2019-02-26 | — | — | CN | claimed |
| EP-0532444-A1 | Process for impregnating wood with plastic material | MADERAS NAVARRA, S.A. (ES) | 1993-03-17 | — | — | EP | claimed |
| US-20230369563-A1 | NEGATIVE ELECTRODE SHEET AND LITHIUM-ION BATTERY INCLUDING SAME | ZHUHAI COSMX BATTERY CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| CN-110431140-A | Fluorescent colorants based on cyanoaryl-substituted naphthoylene benzimidazole compounds | BASF SE | 2019-11-08 | — | — | CN | disclosed |
| CN-110187425-A | Material with anti-blue light function and the protective film using the material | 厦门大学 | 2019-08-30 | — | — | CN | disclosed |
| CN-109963948-A | Method for quantitative amplification | 拜奥法尔诊断有限责任公司 | 2019-07-02 | — | — | CN | disclosed |
| EP-0532444-A1 | Process for impregnating wood with plastic material | MADERAS NAVARRA, S.A. (ES) | 1993-03-17 | — | — | EP | disclosed |
| EP-0532444-A1 | Process for impregnating wood with plastic material | MADERAS NAVARRA, S.A. (ES) | 1993-03-17 | — | — | EP | disclosed |
| US-5054872-A | POLYMERIC OPTICAL WAVEGUIDES AND METHODS OF FORMING THE SAME | IBM CORPORATION (US) | 1991-10-08 | — | — | US | disclosed |
| EP-0446672-A1 | Polymeric optical waveguides and methods of forming the same | International Business Machines Corporation (US) | 1991-09-18 | — | — | EP | disclosed |