Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3438745 | 0.92 | MEN1 (0.59) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL10390473 | 0.90 | MEN1 (0.57) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL7099472 | 0.90 | IDO1 (0.53) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL196951 | 0.89 | IDO1 (0.67) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL9574249 | 0.88 | IDO1 (0.52) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL9262777 | 0.88 | IDO1 (0.52) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL9257411 | 0.88 | IDO1 (0.52) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL1179386 | 0.87 | TDP1 (0.58) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL9258414 | 0.86 | TDP1 (0.52) | IDO1MEN1KMT2ATDP1HRH3 | |
| SCHEMBL3438751 | 0.85 | IDO1 (0.57) | IDO1MEN1KMT2ATDP1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5243076-A | Adrenergic stimulant intermediates | GLAXO GROUP LTD. | 1993-09-07 | — | — | US | disclosed |
| US-5225445-A | Respiratory system disorders | GLAXO GROUP LTD. | 1993-07-06 | — | — | US | disclosed |
| US-5091422-A | Treating inflammatory or allergic skin disease, lowering gastric acidity | GLAXO GROUP LIMITED (GB) | 1992-02-25 | — | — | US | disclosed |
| US-4992474-A | Adrenergic stimulants | GLAXO GROUP LTD. (GB) | 1991-02-12 | — | — | US | disclosed |