Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7870517 | 0.93 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7867688 | 0.92 | SMN1; SMN2 (0.46) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7869440 | 0.91 | MEN1 (0.45) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7870590 | 0.90 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9574710 | 0.90 | EGFR (0.49) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL8869525 | 0.89 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL7862837 | 0.89 | POLB (0.43) | SMN1; SMN2KMT2AMEN1CACNA1BAPBA1 | |
| SCHEMBL7862714 | 0.87 | ALDH1A1 (0.45) | KMT2AMEN1CACNA1BAPBA1CA1 | |
| SCHEMBL7869444 | 0.86 | KMT2A (0.53) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL9018552 | 0.86 | MAPT (0.49) | MAPTNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |