Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.57 |
| ▸ | GSR | P00390 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575152 | 0.90 | HSPA5 (0.50) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL9575286 | 0.87 | GAA (0.43) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL9575147 | 0.85 | GAA (0.62) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL9575245 | 0.82 | GAA (0.64) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL27792864 | 0.82 | GSR (0.54) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL14035134 | 0.82 | GSR (0.57) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL9575255 | 0.81 | GAA (0.59) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL4330346 | 0.81 | GAA (0.51) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL9134773 | 0.80 | GAA (0.56) | GAAGSRKMT2AALDH1A1MAPT | |
| SCHEMBL27582197 | 0.80 | GSR (0.56) | GAAGSRKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4801749-A | Phenolic antioxidant hydrazides | PENNWALT CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |