SCHEMBL9575147

SCHEMBL9575147

CC(C)(C)c1cc(CCNC(=O)C(=O)NN)cc(C(C)(C)C)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.62
KMT2A Q03164 5/20 0.55
MEN1 O00255 4/20 0.47
GSR P00390 2/20 0.44
ALDH1A1 P00352 4/20 0.42
TSHR P16473 3/20 0.42
CYP1A2 P05177 2/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
BLM P54132 2/20 0.42
ATM Q13315 2/20 0.42
HIF1A Q16665 2/20 0.42
NPSR1 Q6W5P4 2/20 0.42
USP2 O75604 1/20 0.42
CYP2D6 P10635 1/20 0.42
MAPT P10636 1/20 0.42
LMNA P02545 3/20 0.41
RECQL P46063 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GMNN O75496 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575245 0.92 GAA (0.64) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL9575255 0.90 GAA (0.59) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL9575137 0.85 GAA (0.57) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL11507342 0.83 GAA (0.72) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL9518040 0.83 GAA (0.61) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL9575134 0.80 GAA (0.50) GAAKMT2AMEN1MAPTLMNA
SCHEMBL3913240 0.79 GAA (0.79) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL4569533 0.79 GAA (0.83) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL9517378 0.79 GAA (0.57) GAAKMT2AMEN1GSRALDH1A1
SCHEMBL11658045 0.78 GAA (0.56) GAAKMT2AMEN1GSRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303280-B1 PHENOLIC ANTIOXIDANT HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1993-03-24 EP disclosed
EP-0303280-A2 Phenolic antioxidant hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4801749-A Phenolic antioxidant hydrazides PENNWALT CORPORATION (US) 1989-01-31 US disclosed