Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 5/20 | 0.31 |
| ▸ | CNR2 | P34972 | 5/20 | 0.31 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575276 | 0.92 | GAA (0.45) | KDM4EGAAALDH1A1MAPK1TDP1 | |
| SCHEMBL9575154 | 0.86 | GAA (0.53) | KDM4EGAAALDH1A1MAPK1TDP1 | |
| SCHEMBL9575477 | 0.81 | GAA (0.43) | KDM4EGAAALDH1A1MAPK1TDP1 | |
| SCHEMBL8335780 | 0.76 | GAA (0.64) | KDM4EGAAALDH1A1MAPK1TDP1 | |
| SCHEMBL11520930 | 0.74 | GAA (0.49) | KDM4EGAAALDH1A1TDP1 | |
| SCHEMBL9742203 | 0.74 | — | — | |
| SCHEMBL9575286 | 0.72 | GAA (0.43) | GAAALDH1A1MAPK1TDP1CYP1A2 | |
| SCHEMBL23539085 | 0.72 | GAA (0.47) | KDM4EGAAALDH1A1MAPK1TDP1 | |
| SCHEMBL11520853 | 0.71 | GAA (0.45) | GAAALDH1A1TDP1 | |
| SCHEMBL11522501 | 0.71 | GAA (0.56) | GAAALDH1A1MAPK1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303280-B1 | PHENOLIC ANTIOXIDANT HYDRAZIDES | ATOCHEM NORTH AMERICA, INC. (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0303280-A2 | Phenolic antioxidant hydrazides | ATOCHEM NORTH AMERICA, INC. (US) | 1989-02-15 | — | — | EP | disclosed |
| US-4801749-A | Phenolic antioxidant hydrazides | PENNWALT CORPORATION (US) | 1989-01-31 | — | — | US | disclosed |