SCHEMBL9575477

SCHEMBL9575477

CCCC(C)(C)c1cc(NC(=O)C(=O)NN)cc(C(C)(C)CCC)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.43
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 3/20 0.43
MAPK1 P28482 1/20 0.41
KDM4E B2RXH2 2/20 0.41
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 2/20 0.31
RECQL P46063 2/20 0.31
AR P10275 2/20 0.31
NSD2 O96028 1/20 0.30
ALPL P05186 1/20 0.30
POLB P06746 1/20 0.30
ALPI P09923 1/20 0.30
MAPT P10636 1/20 0.30
ALPG P10696 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
BLM P54132 1/20 0.30
CASP6 P55212 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9575276 0.88 GAA (0.45) GAAALDH1A1TDP1MAPK1KDM4E
SCHEMBL11521372 0.83 TDP1 (0.46) GAAALDH1A1TDP1KDM4EKMT2A
SCHEMBL8335780 0.82 GAA (0.64) GAAALDH1A1TDP1MAPK1KDM4E
SCHEMBL9575249 0.81 KDM4E (0.42) GAAALDH1A1TDP1MAPK1KDM4E
SCHEMBL11518156 0.80 TDP1 (0.43) GAAALDH1A1TDP1KMT2AMEN1
SCHEMBL11518677 0.80 GAA (0.54) GAAALDH1A1TDP1MAPK1KMT2A
SCHEMBL11518542 0.78 TDP1 (0.41) GAAALDH1A1TDP1RECQLAR
SCHEMBL11521364 0.77 GAA (0.43) GAAALDH1A1TDP1LMNA
SCHEMBL11517617 0.76 GAA (0.42) GAAALDH1A1TDP1KMT2AMEN1
SCHEMBL11517625 0.76 GAA (0.42) GAAALDH1A1TDP1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0303280-B1 PHENOLIC ANTIOXIDANT HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1993-03-24 EP disclosed
EP-0303280-A2 Phenolic antioxidant hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1989-02-15 EP disclosed
US-4801749-A Phenolic antioxidant hydrazides PENNWALT CORPORATION (US) 1989-01-31 US disclosed