SCHEMBL5476725

SCHEMBL5476725

c1cc(C2=NCCN2)ccc1C1=NCCN1

nearest known ligand 0.79

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 13/20 0.79
LMNA P02545 1/20 0.76
RECQL P46063 1/20 0.76
TOP2A P11388 2/20 0.73
TOP2B Q02880 2/20 0.73
HTR1D P28221 1/20 0.70
ADRA1A P35348 1/20 0.70
ALDH1A1 P00352 1/20 0.63
CYP1A2 P05177 1/20 0.63
HPGD P15428 1/20 0.63
CASP1 P29466 1/20 0.63
CASP7 P55210 1/20 0.63
HSD17B10 Q99714 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL523059 0.89 LMNA (0.96) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL2518908 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1886692 0.89 NISCH (1.00) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1685409 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1209074 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL8141372 0.89 NISCH (1.00) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL771337 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL1882160 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL17826831 0.89 NISCH (0.66) NISCHLMNARECQLTOP2ATOP2B
SCHEMBL10507263 0.88 NISCH (1.00) NISCHLMNARECQLTOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3087216-B1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2018-10-10 EP disclosed
US-20160319442-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF DOW INTERNATIONAL TECHNOLOGY CORPORATION 2016-11-03 US disclosed
US-20160319442-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF DOW INTERNATIONAL TECHNOLOGY CORPORATION 2016-11-03 US disclosed
EP-3087216-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF Dow Global Technologies LLC (US) 2016-11-02 EP disclosed
WO-2015100031-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-02 WO disclosed
WO-2015100031-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2015-07-02 WO disclosed
US-7439011-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2008-10-21 US disclosed
US-7439011-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2008-10-21 US disclosed
US-7419774-B2 Photothermographic material and method for processing the same FUJILFILM CORPORATION (JP) 2008-09-02 US disclosed
US-20070197738-A1 Process for making polyesters CITIBANK, N.A., AS COLLATERAL AGENT 2007-08-23 US disclosed
US-7223528-B2 Photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-05-29 US disclosed
US-20070003887-A1 Photothermographic material RIKIO INOUE 2007-01-04 US disclosed
US-20070003887-A1 Photothermographic material RIKIO INOUE 2007-01-04 US disclosed
EP-0493780-B1 Hardener for the preparation of mat coatings basing on epoxy resins SUEDDEUTSCHE KALKSTICKSTOFF (DE) 1995-11-29 EP disclosed
EP-0331507-B1 POLYVINYL CHLORIDE PLASTISOL COMPOSITION ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1993-05-19 EP disclosed
US-5206332-A CURING AGENT FOR THE PRODUCTION OF LOW GLOSS POWDER COATINGS BASED ON EPOXY RESINS SKW TROSTBERG AKTIENGESELLSCHAFT (DE) 1993-04-27 US disclosed
EP-0493780-A2 Hardener for the preparation of mat coatings basing on epoxy resins SKW Trostberg Aktiengesellschaft (DE) 1992-07-08 EP disclosed
US-4977201-A Blended with modified epoxy resin, blocked isocyanate, latent curing for resin as tackifier, automobile undercoatings ASAHI DENKA KOGYO K.K. (JP) 1990-12-11 US disclosed
EP-0331507-A1 Polyvinyl chloride plastisol composition ASAHI DENKA KOGYO KABUSHIKI KAISHA (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160319442-A1 BIS-IMIDAZOLINE COMPOUNDS AS CORROSION INHIBITORS AND PREPARATION THEREOF SOD1, FHIT, TFPI NISCH 49/4885LMNA 2849/4885RECQL 1020/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.