Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | TACR1 | P25103 | 5/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575541 | 0.89 | TSHR (0.56) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9575379 | 0.87 | TSHR (0.41) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9019803 | 0.86 | ALDH1A1 (0.50) | KMT2ACA1CA2CA7CA9 | |
| SCHEMBL9575553 | 0.85 | TSHR (0.47) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9575373 | 0.85 | TSHR (0.47) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9575380 | 0.82 | CA1 (0.46) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9575526 | 0.80 | TSHR (0.45) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL4535810 | 0.80 | TSHR (0.58) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL9575742 | 0.79 | TSHR (0.48) | KMT2ATSHRCA1CA2CA7 | |
| SCHEMBL16183150 | 0.79 | KMT2A (0.51) | KMT2ATSHRCA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |