Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.79 |
| ▸ | METAP2 | P50579 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323798 | 1.00 | REN (0.79) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL14415355 | 1.00 | REN (0.79) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL7296545 | 1.00 | REN (0.79) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL9858453 | 1.00 | REN (0.79) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL7284318 | 1.00 | REN (0.79) | RENMETAP2BCHECHRNB2CHRNB4 | |
| Hydrochloric Acid SCHEMBL7343870 | 0.99 | REN (0.77) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL9858183 | 0.99 | REN (0.77) | RENMETAP2BCHECHRNB2CHRNB4 | |
| SCHEMBL9575444 | 0.99 | REN (0.77) | RENMETAP2BCHECHRNB2CHRNB4 | |
| Acetic Acid SCHEMBL7273459 | 0.97 | REN (0.74) | RENMETAP2BCHE | |
| SCHEMBL9858465 | 0.89 | REN (0.62) | RENMETAP2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258183-B1 | PROCESS FOR THE PREPARATION OF 5-AMINO-4-HYDROXYVALERIC-ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1993-03-17 | — | — | EP | disclosed |
| US-5010189-A | Processes for the preparation of 5-amino-4-hydroxy-valeric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | disclosed |
| US-4898977-A | Processes for the preparation of 5-amino-4-hydroxyvaleric acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0258183-A2 | Process for the preparation of 5-amino-4-hydroxyvaleric-acid derivatives | CIBA-GEIGY AG (CH) | 1988-03-02 | — | — | EP | disclosed |