Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9655860 | 0.82 | CYP3A4 (0.33) | ALDH1A1 | |
| SCHEMBL9575228 | 0.81 | — | — | |
| SCHEMBL9575359 | 0.80 | ELANE (0.42) | MAPT | |
| SCHEMBL18697366 | 0.79 | TPMT (0.41) | TPMTTSHRMRGPRX4MAPTALDH1A1 | |
| SCHEMBL9575148 | 0.78 | CYP4F2 (0.41) | MAPT | |
| SCHEMBL9575641 | 0.77 | MAPT (0.42) | TSHRMAPTRAB9A | |
| SCHEMBL16641111 | 0.76 | — | — | |
| SCHEMBL9575199 | 0.76 | MEN1 (0.41) | TPMTTSHRMAPTALDH1A1 | |
| SCHEMBL9575524 | 0.74 | HPGD (0.33) | TSHRALDH1A1 | |
| SCHEMBL4612658 | 0.73 | TPMT (0.41) | TPMTTSHRMRGPRX4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |
| EP-0249867-B1 | SUBSTITUTED PHENYL ESTERS OF ALPHA-FLUOROACRYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-02 | — | — | EP | disclosed |
| EP-0249867-A2 | Substituted phenyl esters of alpha-fluoroacrylic acid | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-23 | — | — | EP | disclosed |