Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 4/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15834836 | 0.83 | KIF11 (0.43) | ELANEMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5320836 | 0.83 | ELANE (0.44) | ELANEBCHELIPECYP11B1CYP11B2 | |
| SCHEMBL7063178 | 0.83 | ELANE (0.50) | ELANEBCHELIPECYP11B1CYP11B2 | |
| SCHEMBL9575401 | 0.82 | KMT2A (0.41) | ELANEHPGDMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9575641 | 0.80 | MAPT (0.42) | MEN1KMT2ASMN1; SMN2MAPTHTT | |
| SCHEMBL9575635 | 0.80 | TPMT (0.35) | MAPT | |
| SCHEMBL9575396 | 0.80 | LMNA (0.55) | ELANEBCHEKMT2AMAPTCYP1A2 | |
| SCHEMBL9575349 | 0.80 | ELANE (0.39) | ELANEKMT2A | |
| SCHEMBL452065 | 0.80 | ELANE (0.59) | ELANELIPECYP11B1CYP11B2HPGD | |
| SCHEMBL9575390 | 0.80 | LDHA (0.41) | ELANEMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5266668-A | Substituted phenyl α-fluoroacrylates | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-11-30 | — | — | US | disclosed |