Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575685 | 0.86 | GSK3B (0.42) | KMT2AALDH1A1SMN1; SMN2GSK3B | |
| SCHEMBL9575519 | 0.84 | KMT2A (0.46) | MAPTHPGDCYP11B1CYP11B2KMT2A | |
| SCHEMBL9575469 | 0.84 | AKR1C3 (0.47) | MAPTHPGDKMT2AALDH1A1NPC1 | |
| SCHEMBL9575680 | 0.81 | GAA (0.46) | MAPTHPGDKMT2AALDH1A1NPC1 | |
| SCHEMBL9575538 | 0.79 | RXFP1 (0.41) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9797395 | 0.79 | CA1 (0.43) | MAPTHPGDKMT2AALDH1A1CA1 | |
| SCHEMBL9797638 | 0.76 | MAPT (0.42) | MAPTHPGDKMT2AALDH1A1NPC1 | |
| SCHEMBL14454220 | 0.73 | MAPK13 (0.49) | CYP11B1CYP11B2ALDH1A1NPC1RAB9A | |
| SCHEMBL9493141 | 0.73 | GAA (0.49) | MAPTHPGDKMT2AALDH1A1NPC1 | |
| SCHEMBL31186049 | 0.73 | MAPK13 (0.49) | CYP11B1CYP11B2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |