Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | VNN1 | O95497 | 5/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575692 | 0.86 | MAPT (0.40) | GSK3BSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL9575519 | 0.84 | KMT2A (0.46) | VNN1KMT2AALDH1A1 | |
| SCHEMBL9575469 | 0.81 | AKR1C3 (0.47) | KMT2AALDH1A1 | |
| SCHEMBL9797697 | 0.80 | GSK3B (0.43) | GSK3BHTTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9575680 | 0.78 | GAA (0.46) | HTTSMN1; SMN2KMT2AALDH1A1TSHR | |
| SCHEMBL5784328 | 0.74 | ALDH1A1 (0.42) | GSK3BHTTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9575571 | 0.74 | GSK3B (0.51) | GSK3BHTTVNN1MAPK14CLK1 | |
| SCHEMBL9575709 | 0.73 | ELANE (0.41) | GSK3BHTTKDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL9575562 | 0.73 | GSK3B (0.54) | GSK3BHTTVNN1MAPK14CLK1 | |
| SCHEMBL11057542 | 0.73 | GSK3B (0.50) | GSK3BHTTVNN1MAPK14CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0367671-A2 | Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | FOURNIER INDUSTRIE ET SANTE (FR) | 1990-05-09 | — | — | EP | disclosed |