Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIG1 | P18858 | 1/20 | 0.65 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA6 | P23280 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29499085 | 0.84 | LIG1 (0.87) | LIG1STSCA2CA1ALDH1A1 | |
| SCHEMBL21802003 | 0.84 | LIG1 (0.87) | LIG1STSCA2CA1ALDH1A1 | |
| SCHEMBL11692527 | 0.84 | LIG1 (0.67) | LIG1STSCA2CA1ALDH1A1 | |
| SCHEMBL9575571 | 0.81 | GSK3B (0.51) | LIG1GSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL31186049 | 0.81 | MAPK13 (0.49) | CA2CA1CYP11B1CYP11B2GSK3B | |
| SCHEMBL9575857 | 0.81 | GSK3B (0.47) | LIG1CA2CA1CYP11B1CYP11B2 | |
| SCHEMBL14454220 | 0.81 | MAPK13 (0.49) | CA2CA1CYP11B1CYP11B2GSK3B | |
| SCHEMBL11060732 | 0.81 | PARP2 (0.51) | CA2CA1CYP11B1CYP11B2GSK3B | |
| SCHEMBL5558735 | 0.81 | MAPT (0.65) | CA2CA1CYP11B1CYP11B2GSK3B | |
| SCHEMBL9712361 | 0.81 | CA1 (0.47) | LIG1CA2CA1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0367671-A2 | Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | FOURNIER INDUSTRIE ET SANTE (FR) | 1990-05-09 | — | — | EP | disclosed |