Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712361 | 0.83 | CA1 (0.47) | PARP2PARP15PARP10CA1CA2 | |
| SCHEMBL5558735 | 0.83 | MAPT (0.65) | PARP2PARP15PARP10CA1CA2 | |
| SCHEMBL11057542 | 0.82 | GSK3B (0.50) | PARP1GSK3BMAPK14 | |
| SCHEMBL9575745 | 0.81 | LIG1 (0.65) | CA1CA2CYP11B1CYP11B2GSK3B | |
| SCHEMBL14454220 | 0.79 | MAPK13 (0.49) | CA1CA2CYP11B1CYP11B2AKR1C3 | |
| SCHEMBL9575857 | 0.79 | GSK3B (0.47) | PARP2PARP15PARP10CA1CA2 | |
| SCHEMBL31186049 | 0.79 | MAPK13 (0.49) | CA1CA2CYP11B1CYP11B2AKR1C3 | |
| SCHEMBL1466509 | 0.79 | AKR1C3 (0.68) | PARP1AKR1C3CDC25BATMNR4A1 | |
| SCHEMBL7849772 | 0.78 | LIG1 (0.66) | PARP10AKR1C3CDC25BATMNR4A1 | |
| SCHEMBL3215328 | 0.77 | ALDH1A1 (0.61) | CA1CA2GSK3BATMMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447515-A | DIACYLAMINE COMPOUND ADDED | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-08 | — | — | US | disclosed |