Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535810 | 0.94 | TSHR (0.58) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL9575541 | 0.88 | TSHR (0.56) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL9575379 | 0.86 | TSHR (0.41) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL14305766 | 0.85 | TSHR (0.43) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL10581265 | 0.85 | TSHR (0.48) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL9845277 | 0.85 | TSHR (0.48) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL19068463 | 0.84 | CA1 (0.49) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL17770696 | 0.83 | TSHR (0.50) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL828589 | 0.83 | CA1 (0.51) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL8904530 | 0.83 | CA1 (0.51) | TSHRCA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5225550-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED ACYCLIC NUCLEOSIDES, AND INTERMEDIATES OCCURRING THEREIN | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-07-06 | — | — | US | disclosed |
| EP-0464511-A2 | Process for the preparation of acyclic, substituted nucleosides and its intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-01-08 | — | — | EP | disclosed |