Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561568 | 0.78 | HPGD (0.60) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL19666820 | 0.76 | NPC1 (0.44) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL1514997 | 0.74 | NPC1 (1.00) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL29365072 | 0.74 | NPC1 (1.00) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL38652 | 0.74 | NPC1 (1.00) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL29380756 | 0.72 | NPC1 (0.96) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL2526579 | 0.72 | NPC1 (0.96) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL10453973 | 0.72 | NPC1 (0.96) | NPC1RAB9AMAPK1HPGDCYP3A4 | |
| SCHEMBL9551525 | 0.72 | CES2 (0.48) | NPC1MAPK1HPGDCYP3A4ALDH1A1 | |
| SCHEMBL11137371 | 0.71 | CA12 (0.43) | NPC1RAB9AMAPK1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0527274-A1 | Photo-deterioration inhibitor and composition containing the same | DAIKYO GOMU SEIKO LTD. (JP) | 1993-02-17 | — | — | EP | disclosed |