Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575840 | 0.85 | ELANE (0.44) | ELANECYP11B1MAPTCYP11B2KDM4E | |
| SCHEMBL9575709 | 0.84 | ELANE (0.41) | ELANEKDM4EHSD17B10 | |
| SCHEMBL9753203 | 0.82 | TP53 (0.46) | ELANEPTGDR2MAPTMAPK1LMNA | |
| SCHEMBL9575851 | 0.81 | PTGDR2 (0.43) | NCEH1MRGPRX4PTGDR2SLC6A9KDM4E | |
| SCHEMBL6392908 | 0.80 | ELANE (0.59) | ELANEMAPTMAPK1POLBKDM4E | |
| SCHEMBL9491365 | 0.74 | NCEH1 (0.42) | NCEH1CYP11B1PTGDR2CYP11B2KDM4E | |
| SCHEMBL9797353 | 0.74 | VNN1 (0.45) | ELANECYP11B1MAPK1CYP11B2POLB | |
| SCHEMBL28788737 | 0.73 | AR (0.48) | NCEH1CYP11B1MRGPRX4MAPTKMT2A | |
| SCHEMBL9575519 | 0.72 | KMT2A (0.46) | CYP11B1MAPTCYP11B2POLBKMT2A | |
| SCHEMBL7468048 | 0.72 | POLB (0.66) | ELANEMAPTMAPK1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367671-B1 | NOVEL BETA-D-PHENYLTHIOXYLOSIDES, THEIR METHOD OF PREPARATION AND THEIR USE AS PHARMACEUTICALS | FOURNIER INDUSTRIE ET SANTE (FR) | 1993-07-28 | — | — | EP | disclosed |
| US-4960758-A | Antithrombotics | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-02 | — | — | US | disclosed |
| EP-0367671-A2 | Novel beta-D-phenylthioxylosides, their method of preparation and their use as pharmaceuticals | FOURNIER INDUSTRIE ET SANTE (FR) | 1990-05-09 | — | — | EP | disclosed |