Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8244836 | 0.86 | CYP2D6 (0.49) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL8970225 | 0.81 | FFAR1 (0.49) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL10755583 | 0.80 | ADRB3 (0.42) | ADRB2ADRB1ADRB3LMNAACACB | |
| SCHEMBL10581838 | 0.79 | CYP2D6 (0.56) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL18774800 | 0.79 | CYP2D6 (0.47) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL8404165 | 0.79 | CYP2D6 (0.47) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL16845224 | 0.78 | NQO1 (0.56) | ACACB | |
| SCHEMBL1944103 | 0.78 | LDHA (0.57) | NPC1RAB9ATP53ALDH1A1MAPT | |
| SCHEMBL25937506 | 0.78 | NPC1 (0.47) | CYP2D6NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL9575971 | 0.77 | NPC1 (0.49) | CYP2D6NPC1RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0281941-B1 | Coreactive photoinitiators | CIBA GEIGY AG (CH) | 1993-12-08 | — | — | EP | claimed |