Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9576255 | 0.75 | HTT (0.33) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL9719170 | 0.73 | HCAR2 (0.38) | — | |
| SCHEMBL10457568 | 0.73 | HTT (0.38) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL9576324 | 0.73 | HTT (0.38) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL9576361 | 0.71 | HCAR2 (0.40) | — | |
| SCHEMBL9576336 | 0.71 | HTT (0.36) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL9576304 | 0.71 | HCAR2 (0.40) | — | |
| SCHEMBL9576164 | 0.71 | HCAR2 (0.36) | — | |
| SCHEMBL31190307 | 0.69 | HTT (0.40) | HTTNPC1GAASMN1; SMN2 | |
| SCHEMBL8152677 | 0.68 | HCAR2 (0.40) | HTTNPC1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219884-B1 | HARD CONTACT LENS MATERIAL | Tomei Sangyo Kabushiki Kaisha (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5142009-A | Crosslinked blend of fumaric acid diesters | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-4868260-A | OXYGEN PERMEABILITY | TOMEI SANGYO KABUSHIKI KAISHA (JP) | 1989-09-19 | — | — | US | disclosed |
| EP-0219884-A2 | Hard contact lens material | Tomei Sangyo Kabushiki Kaisha (JP) | 1987-04-29 | — | — | EP | disclosed |