SCHEMBL957637

SCHEMBL957637

CCCCCCC(C)C(=O)O.OC1CC2C=CC1C2

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.49
TBXA2R P21731 1/20 0.39
PTGFR P43088 1/20 0.39
PTGER2 P43116 1/20 0.39
GPR84 Q9NQS5 4/20 0.38
CA1 P00915 2/20 0.38
FFAR1 O14842 2/20 0.38
MAPT P10636 1/20 0.37
LCK P06239 1/20 0.37
PPARD Q03181 1/20 0.37
ZDHHC20 Q5W0Z9 1/20 0.37
ZDHHC2 Q9UIJ5 1/20 0.37
FFAR4 Q5NUL3 1/20 0.36
FAAH O00519 1/20 0.35
LTA4H P09960 1/20 0.35
TBXAS1 P24557 2/20 0.35
BLM P54132 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1477158 0.81 ACE2 (0.56) ACE2GPR84CA1FFAR1MAPT
SCHEMBL1477507 0.81 ACE2 (0.56) ACE2GPR84CA1FFAR1MAPT
SCHEMBL1477205 0.81 ACE2 (0.56) ACE2GPR84CA1FFAR1MAPT
SCHEMBL1476651 0.81 ACE2 (0.56) ACE2GPR84CA1FFAR1MAPT
SCHEMBL958080 0.77 KDM4E (0.39)
SCHEMBL7080552 0.75 ACE2 (0.80) ACE2GPR84CA1FFAR1MAPT
SCHEMBL2054033 0.75 ACE2 (0.80) ACE2GPR84CA1FFAR1MAPT
Dodecane SCHEMBL14691319 0.75 ACE2 (0.80) ACE2GPR84CA1FFAR1MAPT
SCHEMBL7146627 0.75 ACE2 (0.80) ACE2GPR84CA1FFAR1MAPT
SCHEMBL6657056 0.75 ACE2 (0.80) ACE2GPR84CA1FFAR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2248839-B1 CRYSTALLINE NORBORNENE RING-OPENING POLYMER HYDRIDE AND MOLDED ARTICLE OF SAME ZEON CORP (JP) 2018-03-28 EP disclosed
EP-2128196-B1 POLYMER COMPOSITION AND USE THEREOF ZEON CORP (JP) 2016-10-26 EP disclosed
US-8277914-B2 Polymer composition and use thereof ZEON CORPORATION (JP) 2012-10-02 US disclosed
US-8053531-B2 Hydrogenated crystalline norbornene ring-opening polymer and molded article ZEON CORPORATION (JP) 2011-11-08 US disclosed
US-20110021731-A1 HYDROGENATED CRYSTALLINE NORBORNENE RING-OPENING POLYMER AND MOLDED ARTICLE ZEON CORPORATION (JP) 2011-01-27 US disclosed
EP-2248839-A1 CRYSTALLINE NORBORNENE RING-OPENING POLYMER HYDRIDE AND MOLDED ARTICLE OF SAME Zeon Corporation (JP) 2010-11-10 EP disclosed
US-20100092712-A1 POLYMER COMPOSITION AND USE THEREOF ZEON CORPORATION (JP) 2010-04-15 US disclosed
EP-2128196-A1 POLYMER COMPOSITION AND USE THEREOF ZEON CORPORATION (JP) 2009-12-02 EP disclosed