Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 3/20 | 0.41 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14151095 | 1.00 | TBXAS1 (0.45) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL14151094 | 1.00 | TBXAS1 (0.45) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL9577009 | 1.00 | TBXAS1 (0.45) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL23829915 | 0.91 | — | — | |
| SCHEMBL3247704 | 0.91 | — | — | |
| SCHEMBL29091291 | 0.90 | PTPN1 (0.58) | PTPN1BLMLMNAAPEX1NPSR1 | |
| SCHEMBL1815001 | 0.88 | PTPN1 (0.52) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL7856296 | 0.88 | PTPN1 (0.52) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL7856305 | 0.88 | PTPN1 (0.52) | TBXAS1PTPN1BLMGABRR1GABRR2 | |
| SCHEMBL7856285 | 0.88 | PTPN1 (0.52) | TBXAS1PTPN1BLMGABRR1GABRR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0379982-B1 | Method of preparation of 8-hydroxyoctanoic acid | NATTERMANN A & CIE (DE) | 1993-12-08 | — | — | EP | disclosed |
| US-5248798-A | METHOD OF PREPARATION OF 8-HYDROXYOCTANOIC ACID | NATTERMAN, A. & CIE. GMBH (DE) | 1993-09-28 | — | — | US | disclosed |
| EP-0454743-A1 | METHOD OF PREPARATION OF 8-HYDROXYOCTANOIC ACID | A. Nattermann & Cie. GmbH (DE) | 1991-11-06 | — | — | EP | disclosed |
| EP-0379982-A1 | Method of preparation of 8-hydroxyoctanoic acid | A. Nattermann & Cie. GmbH (DE) | 1990-08-01 | — | — | EP | disclosed |
| WO-1990008125-A2 | METHOD OF PREPARATION OF 8-HYDROXYOCTANOIC ACID | NATTERMANN, A. & CIE. GMBH (DE) | 1990-07-26 | — | — | WO | disclosed |