SCHEMBL9577017

SCHEMBL9577017

S=C1NCCCCCNC(=S)SS1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FKBP5 Q13451 1/20 0.32
CRBN Q96SW2 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4651720 0.97 FKBP5 (0.33) FKBP5CRBN
SCHEMBL400516 0.89
SCHEMBL5918490 0.86 FKBP5 (0.31) FKBP5CRBN
SCHEMBL5470783 0.84 SMN1; SMN2 (0.35)
SCHEMBL9716180 0.81 SMN1; SMN2 (0.33)
SCHEMBL6053394 0.79 FKBP5 (0.33) FKBP5CRBN
SCHEMBL9516315 0.73 SMN1; SMN2 (0.32)
SCHEMBL30331251 0.72
SCHEMBL11166997 0.71 SMN1; SMN2 (0.48) FKBP5CRBNALDH1A1
SCHEMBL8961691 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5219904-A With organic peroxide NIPPON MEKTRON LIMITED (JP) 1993-06-15 US disclosed
US-5159026-A Containing halogen and peroxy compound NIPPON MEKTRON, LIMITED (JP) 1992-10-27 US disclosed
US-4254016-A AMINO ACID HEAT STABILIZING ADDITIVE SANYO TRADING CO., LTD. (JP) 1981-03-03 US disclosed