SCHEMBL9577112

SCHEMBL9577112

CNS(=O)(=O)c1cc(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA12 O43570 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA13 Q8N1Q1 2/20 0.41
CA14 Q9ULX7 2/20 0.41
CA5B Q9Y2D0 2/20 0.41
CA3 P07451 1/20 0.41
GSTO1 P78417 1/20 0.41
LMNA P02545 2/20 0.40
CYP3A4 P08684 2/20 0.40
VCAM1 P19320 1/20 0.39
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
PTGES2 Q9H7Z7 1/20 0.35
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11689857 0.82 CA1 (0.41) CA1CA2CA12CA4CA6
SCHEMBL6766698 0.79 PKM (0.45) CA1CA2CA12CA4CA6
SCHEMBL2371939 0.78 KMT2A (0.46) CA1CA2CA12CA4CA6
SCHEMBL11514167 0.77 KMT2A (0.45) CA1CA2CA12CA4CA6
SCHEMBL11514174 0.77 CA12 (0.47) CA1CA2CA12CA4CA6
SCHEMBL28621237 0.76 CA1 (0.40) CA1CA2CA12CA4CA6
SCHEMBL10455146 0.76 POLB (0.55) CA1CA2CA12CA9CYP3A4
SCHEMBL11929253 0.76 CA1 (0.68) CA1CA2CA12CA4CA6
SCHEMBL29859906 0.75 CYP3A4 (0.50) CA1CA2CA12CA4CA6
SCHEMBL17310965 0.75 CYP3A4 (0.50) CA1CA2CA12CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264474-A Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds MTM AMERICAS INC. (US) 1993-11-23 US disclosed
US-4957957-A Polymer compositions containing aromatic sulfonamide ETHYL CORPORATION (US) 1990-09-18 US disclosed