Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.59 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.59 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | SCN1A | P35498 | 3/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577146 | 1.00 | RECQL (0.78) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9577217 | 1.00 | RECQL (0.78) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL10455162 | 1.00 | RECQL (0.78) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL10453957 | 0.88 | RECQL (0.59) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9577176 | 0.87 | RECQL (0.67) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL10455059 | 0.87 | RECQL (0.67) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9577149 | 0.87 | RECQL (0.67) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9577082 | 0.87 | RECQL (0.67) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL9577185 | 0.86 | RECQL (0.74) | RECQLCYP3A4TSHRMEN1KMT2A | |
| SCHEMBL2229994 | 0.81 | RECQL (0.88) | RECQLCYP3A4TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |