SCHEMBL9577152

SCHEMBL9577152

CCCCCCCCCNS(=O)(=O)c1ccc(Br)c(Br)c1Cl

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.62
ALDH1A1 P00352 4/20 0.54
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2C19 P33261 2/20 0.54
MEN1 O00255 2/20 0.53
TSHR P16473 2/20 0.53
KMT2A Q03164 2/20 0.53
HTT P42858 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TP53 P04637 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
POLB P06746 2/20 0.47
CA12 O43570 2/20 0.46
CA9 Q16790 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
FABP4 P15090 1/20 0.42
PDK1 Q15118 2/20 0.42
PDK2 Q15119 2/20 0.42
PDK3 Q15120 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9577082 0.87 RECQL (0.67) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577149 0.87 RECQL (0.67) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577176 0.87 RECQL (0.67) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL10455059 0.87 RECQL (0.67) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577185 0.83 RECQL (0.74) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577122 0.81 CYP3A4 (0.62) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577229 0.81 RECQL (0.57) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577137 0.80 RECQL (0.78) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL10455162 0.80 RECQL (0.78) RECQLALDH1A1CYP1A2CYP3A4CYP2C19
SCHEMBL9577146 0.80 RECQL (0.78) RECQLALDH1A1CYP1A2CYP3A4CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264474-A Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds MTM AMERICAS INC. (US) 1993-11-23 US disclosed
US-4957957-A Polymer compositions containing aromatic sulfonamide ETHYL CORPORATION (US) 1990-09-18 US disclosed