SCHEMBL9577219

SCHEMBL9577219

O=S(=O)(NCCCCCCNS(=O)(=O)c1cc(Cl)ccc1Cl)c1cc(Cl)ccc1Cl

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.73
MCL1 Q07820 3/20 0.56
CCR1 P32246 1/20 0.55
TSHR P16473 4/20 0.54
HPGD P15428 1/20 0.54
POLB P06746 1/20 0.54
RAB9A P51151 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.50
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
TP53 P04637 4/20 0.48
CYP3A4 P08684 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C19 P33261 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CYP2D6 P10635 2/20 0.48
CYP2C9 P11712 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL197333 0.92 GAA (0.68) GAAMCL1CCR1TSHRHPGD
SCHEMBL197721 0.92 GAA (0.68) GAAMCL1CCR1TSHRHPGD
SCHEMBL9577232 0.91 GAA (0.69) GAAMCL1CCR1TSHRHPGD
SCHEMBL5324394 0.85 GAA (0.62) GAAMCL1CCR1TSHRHPGD
SCHEMBL3717918 0.85 GAA (0.67) GAAMCL1CCR1TSHRHPGD
SCHEMBL29456580 0.83 GAA (0.61) GAAMCL1CCR1TSHRHPGD
SCHEMBL14063613 0.83 GAA (0.61) GAAMCL1CCR1TSHRHPGD
SCHEMBL28582158 0.81 GAA (0.57) GAAMCL1TSHRHPGDPOLB
SCHEMBL9577182 0.80 POLB (0.50) GAATSHRPOLBTP53CYP3A4
SCHEMBL198691 0.78 GAA (0.58) GAAMCL1TSHRHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5264474-A Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds MTM AMERICAS INC. (US) 1993-11-23 US disclosed
US-4981890-A POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE ETHYL CORPORATION (US) 1991-01-01 US disclosed
US-4957958-A IMPROVED MELT FLOW ETHYL CORPORATION (US) 1990-09-18 US disclosed