Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | THPO | P40225 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577136 | 0.90 | POLB (0.54) | POLBGAACYP3A4KMT2ACYP1A2 | |
| SCHEMBL9577219 | 0.80 | GAA (0.73) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL11398952 | 0.80 | TSHR (0.54) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL11689726 | 0.76 | CYP3A4 (0.49) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL11684878 | 0.76 | GAA (0.43) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL11683784 | 0.76 | KMT2A (0.40) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL11517794 | 0.76 | KMT2A (0.40) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL8980455 | 0.75 | HTR7 (0.67) | — | |
| SCHEMBL11687579 | 0.75 | CYP1A2 (0.48) | POLBGAACYP3A4KMT2ATP53 | |
| SCHEMBL10455035 | 0.75 | TSHR (0.57) | POLBGAACYP3A4KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4981890-A | POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE | ETHYL CORPORATION (US) | 1991-01-01 | — | — | US | disclosed |
| US-4957958-A | IMPROVED MELT FLOW | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |