Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.34 |
| ▸ | ADH1C | P00326 | 1/20 | 0.34 |
| ▸ | ADH1A | P07327 | 1/20 | 0.34 |
| ▸ | ADH4 | P08319 | 1/20 | 0.34 |
| ▸ | ADH7 | P40394 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9442352 | 0.98 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL1901583 | 0.98 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL7173408 | 0.92 | TSHR (0.38) | TSHROPRM1DNM1ADH1BADH1C | |
| SCHEMBL7698918 | 0.90 | DNM1 (0.40) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL13279660 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL9014021 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL1900761 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL10782729 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL17336107 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 | |
| SCHEMBL19511992 | 0.88 | TSHR (0.42) | TSHROPRM1DNM1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |