Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.53 |
| ▸ | UBE2N | P61088 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577453 | 0.88 | EPHX1 (0.53) | EPHX1CHRM1UBE2N | |
| SCHEMBL9577478 | 0.88 | EPHX1 (0.53) | EPHX1CHRM1UBE2NPKM | |
| SCHEMBL9577277 | 0.88 | EPHX1 (0.53) | EPHX1CHRM1UBE2NCYP1A2 | |
| SCHEMBL3079795 | 0.83 | EPHX1 (0.71) | EPHX1CHRM1UBE2NCYP1A2ACP3 | |
| SCHEMBL27600068 | 0.83 | EPHX1 (0.71) | EPHX1CHRM1UBE2NCYP1A2ACP3 | |
| SCHEMBL599399 | 0.83 | EPHX1 (0.71) | EPHX1CHRM1UBE2NCYP1A2ACP3 | |
| SCHEMBL67234 | 0.83 | EPHX1 (0.71) | EPHX1CHRM1UBE2NCYP1A2ACP3 | |
| Hydrochloric Acid SCHEMBL933353 | 0.82 | EPHX1 (0.69) | EPHX1CHRM1UBE2NCYP1A2ALPI | |
| SCHEMBL1234701 | 0.82 | EPHX1 (0.69) | EPHX1CHRM1UBE2NCYP1A2ACP3 | |
| SCHEMBL9796627 | 0.81 | EPHX1 (0.62) | EPHX1CHRM1UBE2NCYP1A2ACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |
| US-4447644-A | Method for preparation of arylpyruvic acid | DYNAMIT NOBEL AG (DE) | 1984-05-08 | — | — | US | disclosed |
| US-4152352-A | PRODUCTION OF ARYLPYRUVIC ACIDS | RHONE-POULENC INDUSTRIES (FR) | 1979-05-01 | — | — | US | disclosed |