Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | UBE2N | P61088 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577404 | 0.88 | EPHX1 (0.67) | EPHX1CHRM1UBE2NPKM | |
| SCHEMBL27871545 | 0.86 | MEN1 (0.59) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL22394826 | 0.86 | SMN1; SMN2 (0.56) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL3371227 | 0.85 | ESR1 (0.62) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL11021257 | 0.83 | EPHX1 (0.77) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL9577453 | 0.83 | EPHX1 (0.53) | EPHX1ALDH1A1CHRM1UBE2N | |
| SCHEMBL22394804 | 0.81 | ESR1 (0.65) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL27875737 | 0.79 | EPHX1 (0.56) | EPHX1MEN1KMT2APSMB5ALDH1A1 | |
| SCHEMBL29152992 | 0.79 | P4HTM (0.56) | EPHX1MEN1KMT2ACHRM1SMN1; SMN2 | |
| SCHEMBL5145520 | 0.78 | ESR1 (0.50) | EPHX1MEN1KMT2APSMB5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407588-B1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEM RES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5028738-A | Process for producing 2-oxo-3-aromatic carboxylic acid derivatives | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-07-02 | — | — | US | disclosed |
| EP-0407588-A1 | PROCESS FOR PRODUCING 2-OXO-3-AROMATIC CARBOXYLIC ACID DERIVATIVES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-01-16 | — | — | EP | disclosed |