SCHEMBL9577481

SCHEMBL9577481

CC(O)(CCO)c1cccc(OCc2ccc3ccccc3c2)c1

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 9/20 0.55
F2 P00734 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9311160 0.90 ALOX5 (0.55) ALOX5F2
SCHEMBL10434695 0.88 ALOX5 (0.53) ALOX5
SCHEMBL9577637 0.87 ALOX5 (0.53) ALOX5F2
SCHEMBL9368879 0.85 ALOX5 (0.56) ALOX5F2
SCHEMBL9577540 0.84 ALOX5 (0.53) ALOX5F2
SCHEMBL9186373 0.83 ALOX5 (0.52) ALOX5
SCHEMBL9184603 0.83 ALOX5 (0.52) ALOX5F2
SCHEMBL278302 0.83 ALOX5 (0.63) ALOX5
SCHEMBL9080859 0.81 ALOX5 (0.58) ALOX5F2
SCHEMBL9183068 0.80 ALOX5 (0.53) ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5214069-A Lipoxygenase inhibitors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-05-25 US disclosed
US-5132328-A Lipoxygenase inhibitors as antiinflammatory agents or antiallergens IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-07-21 US disclosed
EP-0375368-A2 Alcohol and ether derivatives ZENECA LIMITED (GB) 1990-06-27 EP disclosed