Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911726 | 0.83 | KMT2A (0.62) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL5772077 | 0.83 | KMT2A (0.62) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL2381049 | 0.83 | KMT2A (0.60) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL11603161 | 0.82 | KMT2A (0.63) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL20604382 | 0.81 | KMT2A (0.62) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL20604383 | 0.81 | KMT2A (0.62) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL20816018 | 0.81 | KMT2A (0.57) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL4596162 | 0.81 | KMT2A (0.57) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL5494784 | 0.81 | KMT2A (0.64) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 | |
| SCHEMBL28290141 | 0.81 | KMT2A (0.57) | KMT2ASMN1; SMN2NR4A2MAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214069-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |