Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9185100 | 0.87 | MRGPRX4 (0.58) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL2503352 | 0.87 | MAOB (0.69) | MRGPRX4MAOBNR4A2PTPN1SMPD1 | |
| SCHEMBL9226928 | 0.85 | MRGPRX4 (0.60) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL9599197 | 0.85 | MRGPRX4 (0.55) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL9186121 | 0.84 | MAOB (0.74) | MRGPRX4F2MAOBMAOA | |
| SCHEMBL9366253 | 0.83 | MRGPRX4 (0.48) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL10662840 | 0.81 | THRA (0.53) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL4638462 | 0.81 | F2 (0.68) | MRGPRX4F2MAOBNR4A2 | |
| SCHEMBL10431898 | 0.80 | MRGPRX4 (0.46) | MRGPRX4F2MAOBNR4A2PTPN1 | |
| SCHEMBL9079254 | 0.80 | MAPT (0.59) | MRGPRX4F2MAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5214069-A | Lipoxygenase inhibitors | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-05-25 | — | — | US | disclosed |
| US-5132328-A | Lipoxygenase inhibitors as antiinflammatory agents or antiallergens | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-21 | — | — | US | disclosed |
| EP-0375368-A2 | Alcohol and ether derivatives | ZENECA LIMITED (GB) | 1990-06-27 | — | — | EP | disclosed |