Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.50 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | OXER1 | Q8TDS5 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
| ▸ | F3 | P13726 | 3/20 | 0.36 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9577751 | 1.00 | GRIK1 (0.50) | GRIK1GRIK2FPR2GPR84FFAR1 | |
| SCHEMBL29973358 | 0.82 | PPARA (0.58) | FPR2FFAR1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL4891721 | 0.82 | GRIK1 (0.55) | GRIK1GRIK2FPR2FFAR1ALDH1A1 | |
| SCHEMBL4891724 | 0.82 | GRIK1 (0.55) | GRIK1GRIK2FPR2FFAR1ALDH1A1 | |
| SCHEMBL10457604 | 0.82 | GRIK1 (0.55) | GRIK1GRIK2FPR2FFAR1ALDH1A1 | |
| SCHEMBL9565275 | 0.82 | GPR84 (0.42) | GPR84FFAR1OR51E2ALDH1A1MAPT | |
| SCHEMBL9565274 | 0.82 | GPR84 (0.42) | GPR84FFAR1OR51E2ALDH1A1MAPT | |
| SCHEMBL3267543 | 0.79 | F7 (0.50) | GPR84FFAR1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL9577773 | 0.79 | F7 (0.50) | GPR84FFAR1ALDH1A1MAPTCYP19A1 | |
| SCHEMBL9565293 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5108751-A | COSMETIC COMPOSITION COMPRISING 2-HYDROXYALKENOIC ACIDS OR A MIXTURE THEREOF | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1992-04-28 | — | — | US | claimed |
| EP-0442708-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1991-08-21 | — | — | EP | claimed |
| US-5227503-A | 2-Hydroxyalkenoic acids | CHESEBROUGH POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1993-07-13 | — | — | US | disclosed |
| US-5108751-A | COSMETIC COMPOSITION COMPRISING 2-HYDROXYALKENOIC ACIDS OR A MIXTURE THEREOF | CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) | 1992-04-28 | — | — | US | disclosed |
| EP-0442708-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1991-08-21 | — | — | EP | disclosed |