Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 20/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 16/20 | 0.59 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1237576 | 0.87 | OPRD1 (0.80) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| Lithium Ion SCHEMBL7399401 | 0.86 | OPRD1 (0.54) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| Lithium Ion SCHEMBL4283263 | 0.78 | OPRD1 (0.56) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| SCHEMBL9845357 | 0.77 | OPRD1 (0.45) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| SCHEMBL1237845 | 0.77 | OPRD1 (0.45) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| SCHEMBL3696965 | 0.76 | OPRD1 (0.54) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| SCHEMBL19289109 | 0.75 | OPRD1 (0.66) | OPRD1KCNH2OPRK1CYP2D6OPRM1 | |
| SCHEMBL14666752 | 0.75 | OPRD1 (0.42) | OPRD1KCNH2OPRK1CYP2D6 | |
| SCHEMBL14666701 | 0.75 | OPRD1 (0.40) | OPRD1KCNH2OPRK1CYP2D6 | |
| SCHEMBL467151 | 0.75 | OPRD1 (1.00) | OPRD1KCNH2OPRK1CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5183924-A | Anticholesterol agents, antithrombotics, fungicides | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1993-02-02 | — | — | US | disclosed |
| US-5082859-A | Anticholesterol, anticoagulant, fungicide | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1992-01-21 | — | — | US | disclosed |