SCHEMBL9577802

SCHEMBL9577802

Cc1ccccc1Cc1cccc(C)c1Cl

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.43
P2RX7 Q99572 4/20 0.39
AR P10275 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 1/20 0.38
ACHE P22303 1/20 0.38
GPR84 Q9NQS5 1/20 0.37
CHRM2 P08172 1/20 0.37
PTGS1 P23219 1/20 0.37
PTGS2 P35354 1/20 0.37
MAPT P10636 1/20 0.37
KDM4E B2RXH2 1/20 0.37
LMNA P02545 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
TYMP P19971 1/20 0.37
CNR2 P34972 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16933811 0.88 PNMT (0.52) TAAR1P2RX7KDM4EALDH1A1
SCHEMBL11030386 0.85 NR1H2 (0.45) CYP3A4CYP2C19TSHRHPGD
SCHEMBL26849008 0.85 PNMT (0.54) TAAR1P2RX7KDM4EALDH1A1
SCHEMBL29477327 0.83 TAAR1 (0.56) TAAR1P2RX7ARTSHRACHE
SCHEMBL2090458 0.83 TAAR1 (0.56) TAAR1P2RX7ARTSHRACHE
SCHEMBL27275413 0.82 PNMT (0.41) TAAR1P2RX7PTGS2LMNAALDH1A1
SCHEMBL11200954 0.81 TAAR1 (0.54) TAAR1P2RX7ARTSHRACHE
SCHEMBL29772212 0.81 TAAR1 (0.54) TAAR1P2RX7ARTSHRACHE
SCHEMBL253441 0.80 TAAR1 (0.50) TAAR1LMNACNR2
SCHEMBL22508625 0.79 PNMT (0.34) TAAR1P2RX7GPR84LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5117215-A None JP disclosed
JP-H05117215-A SYNTHESIS OF 1-AMINOANTHRAQUINONE HOECHST CELANESE CORP 1993-05-14 JP disclosed