Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.56 |
| ▸ | CES1 | P23141 | 4/20 | 0.56 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 11/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167301 | 0.98 | CES2 (0.58) | CES2CES1PPARGPPARATRPA1 | |
| SCHEMBL14167302 | 0.98 | CES2 (0.58) | CES2CES1PPARGPPARATRPA1 | |
| SCHEMBL14166541 | 0.87 | FABP3 (0.62) | PPARGPPARAPPARDTDP1MEN1 | |
| SCHEMBL14166542 | 0.87 | FABP3 (0.62) | PPARGPPARAPPARDTDP1MEN1 | |
| SCHEMBL14166781 | 0.87 | FABP3 (0.62) | PPARGPPARAPPARDTDP1MEN1 | |
| SCHEMBL14167141 | 0.85 | FFAR1 (0.61) | CES2CES1GPR84FFAR1FFAR4 | |
| SCHEMBL14166951 | 0.85 | FFAR1 (0.61) | CES2CES1GPR84FFAR1FFAR4 | |
| SCHEMBL14166751 | 0.82 | FABP3 (0.66) | PPARGPPARAPPARDTSHRALDH1A1 | |
| SCHEMBL11386228 | 0.82 | — | — | |
| SCHEMBL5822027 | 0.74 | CES2 (0.48) | CES2CES1AKR1B1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5148421-A | — | — | None | — | — | JP | disclosed |
| JP-H05148421-A | BLEND FROM POLYARYLENE SULFIDE, POLYOLEFIN AND NITRO COMPOUND | BAYER AG | 1993-06-15 | — | — | JP | disclosed |
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |