Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9578882 | 0.86 | KMT2A (0.47) | SMN1; SMN2MAPK1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL10551003 | 0.83 | ASAH1 (0.47) | MAPK1KMT2AALDH1A1RAB9AMEN1 | |
| SCHEMBL9579226 | 0.81 | ASAH1 (0.53) | MAPK1KMT2AALDH1A1MEN1L3MBTL1 | |
| SCHEMBL9578772 | 0.77 | ASAH1 (0.67) | ALDH1A1LMNAASAH1HTTADORA2A | |
| SCHEMBL9578721 | 0.74 | ALDH1A1 (0.65) | SMN1; SMN2MAPK1KMT2AALDH1A1LMNA | |
| Benomyl SCHEMBL8819362 | 0.73 | TSHR (0.80) | KMT2AALDH1A1LMNANPC1RAB9A | |
| SCHEMBL30670383 | 0.71 | KMT2A (0.54) | SMN1; SMN2MAPK1KMT2AALDH1A1LMNA | |
| Benzimidazole SCHEMBL10781773 | 0.71 | ASAH1 (0.49) | ALDH1A1LMNANPC1RAB9AL3MBTL1 | |
| SCHEMBL30846021 | 0.69 | KMT2A (0.52) | KMT2AALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL29195620 | 0.69 | KMT2A (0.52) | KMT2AALDH1A1LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0256789-B1 | SUBSTITUTED BENZIMIDAZOLE FUNGICIDE | HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) | 1993-05-05 | — | — | EP | disclosed |
| US-4857541-A | APPLYING TO BENOMYL RESISTANT FUNGI | CANADIAN PATENTS AND DEVELOPMENT LIMITED/SOCIETE CANADIENNE DES BREVETS ET D'EXPLOITATION LIMITEE (CA) | 1989-08-15 | — | — | US | disclosed |
| EP-0256789-A1 | Substituted benzimidazole fungicide | HER MAJESTY IN RIGHT OF CANADA AS REPRESENTED BY THE MINISTER OF AGRICULTURE (CA) | 1988-02-24 | — | — | EP | disclosed |