Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9579397 | 0.78 | MAPT (0.66) | ALDH1A1SMN1; SMN2POLBMAPK1KDM4E | |
| SCHEMBL9579315 | 0.78 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL2568689 | 0.78 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL4697006 | 0.77 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL19864498 | 0.77 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL4080193 | 0.77 | MAPT (0.64) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL4089872 | 0.77 | MAPT (0.64) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL9043266 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL6191426 | 0.76 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 | |
| SCHEMBL8417411 | 0.76 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2GAAPOLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242919-A | Antiinflammatory agents or hypotensive agents | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-09-07 | — | — | US | disclosed |
| US-5055474-A | Antihypoxia, hypotensive, antiinflammatory agents; anoxia treatment | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-08 | — | — | US | disclosed |
| EP-0173331-B1 | 2,3-DIHYDRO-1H-INDENE DERIVATIVES, A PROCESS FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4895847-A | ANTIHYPOXIC, ANTIINFLAMMATORY, HYPOTENSIVE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| US-4788130-A | ANTIHYDOXIC, HYPOTENSIVE, ANTIINFLAMMATORY AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-29 | — | — | US | disclosed |
| EP-0173331-A2 | 2,3-Dihydro-1H-indene derivatives, a process for preparing them and pharmaceutical compositions containing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-03-05 | — | — | EP | disclosed |
| US-3973981-A | PHTHALOCYANINE DYES, PAINTS, INKS | TOYO INK MANUFACTURING CO., LTD. (JA) | 1976-08-10 | — | — | US | disclosed |