Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 4/20 | 0.59 |
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | AXL | P30530 | 1/20 | 0.55 |
| ▸ | KDR | P35968 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.55 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.55 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.55 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 3/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580097 | 0.95 | NPC1L1 (0.60) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL9580104 | 0.95 | NPC1L1 (0.60) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL9580355 | 0.95 | NPC1L1 (0.60) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL9580360 | 0.95 | NPC1L1 (0.60) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL17817535 | 0.90 | NPC1L1 (0.62) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL17817525 | 0.90 | NPC1L1 (0.62) | NPC1L1IGF1RMETSRCAXL | |
| SCHEMBL16225645 | 0.84 | NPC1L1 (0.66) | NPC1L1CYP2D6CYP2C19CDC25ACDC25B | |
| SCHEMBL16225777 | 0.84 | NPC1L1 (0.66) | NPC1L1CYP2D6CYP2C19CDC25ACDC25B | |
| SCHEMBL7117472 | 0.84 | NPC1L1 (0.66) | NPC1L1CYP2D6CYP2C19CDC25ACDC25B | |
| SCHEMBL16226011 | 0.84 | NPC1L1 (0.66) | NPC1L1CYP2D6CYP2C19CDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | claimed |
| EP-0562849-A2 | Steroid derivatives | ELI LILLY AND COMPANY (US) | 1993-09-29 | — | — | EP | disclosed |