Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 4/20 | 0.30 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | PPARD | Q03181 | 2/20 | 0.30 |
| ▸ | PPARA | Q07869 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 2/20 | 0.30 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9580493 | 0.90 | HPGD (0.41) | KDM4EHPGDLMNASMN1; SMN2TRPV1 | |
| SCHEMBL9580471 | 0.81 | HPGD (0.32) | HPGDSMN1; SMN2TRPV1 | |
| SCHEMBL9517809 | 0.81 | CETP (0.40) | KDM4EHPGDLMNASMN1; SMN2CNR2 | |
| SCHEMBL9516776 | 0.81 | CETP (0.40) | KDM4EHPGDLMNASMN1; SMN2CNR2 | |
| SCHEMBL9516782 | 0.81 | CETP (0.40) | KDM4EHPGDLMNASMN1; SMN2CNR2 | |
| SCHEMBL9430134 | 0.78 | HPGD (0.42) | KDM4EHPGDLMNASMN1; SMN2TRPV1 | |
| SCHEMBL9580671 | 0.78 | HPGD (0.42) | KDM4EHPGDLMNASMN1; SMN2TRPV1 | |
| SCHEMBL9430398 | 0.78 | HPGD (0.42) | KDM4EHPGDLMNASMN1; SMN2TRPV1 | |
| SCHEMBL9580457 | 0.78 | HPGD (0.42) | KDM4EHPGDLMNASMN1; SMN2TRPV1 | |
| SCHEMBL9516830 | 0.75 | EPHX2 (0.34) | KDM4EHPGDLMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | claimed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | claimed |
| US-5202356-A | Insecticides, miticides | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-04-13 | — | — | US | disclosed |
| EP-0369762-A1 | Pesticides | ROUSSEL-UCLAF (FR) | 1990-05-23 | — | — | EP | disclosed |